Anti-BCL2L10 (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution

General description

BCL2L10 belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of BCL2L10 gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation.

Immunogen

BCL2L10 (NP_065129, 105-138)This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the Center region of human BCL2L10.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.